A publication in the February 29, 2012 issue of the
British Journal of
Cancer contains a previously
unexplored etiology for Pancreatic Cancer's
(Br J Cancer. 2012 Feb 28;106(5):1004-10)
measured levels of insulin-like growth
factor-1 (IGF-1) and insulin-like
binding protein (IGFBP) in 844 subjects; 422
with pancreatic cancer, and 422 subjects
without cancer which made up the
The researchers did not find a relationship with
IGF-I levels and pancreatic cancer, or with IGFBP
levels and pancreatic
cancer, but they did find
a fascinating relationship between possible
consumption and pancreatic cancer.
IGF-I has been
identified as a key factor in the
growth of every human cancer. We
IGF-I in many of our tissues and organs. We also
manufacture the binding site receptors for these
growth hormones to
IGF-I is identical in humans and cows.
hormone (bGH) human growth hormone
(hGH) both have exactly 191 amino
acids making up
their structure, but the sequence of those amino
acids differs between the two species by a factor
of 35 percent.
Human IGF-I and bovine IGF-1 both have 70 amino
acids in their structure,
and miraculously, the
sequence of amino acids on their protein chains
When we humans consume IGF-I in cow's milk, we do
without also consuming the binding proteins
which are located within a
So, our bodies become flooded with additional
which we manufacture, and there becomes
a dramatic proportional increase
of IGF-I to
IGFBP in our own systems.
Here is the remarkable
finding from the British
Journal of Cancer study.
that pancreatic cancer patients
had extremely low levels of IGF binding
relation to circulating IGF-1. These patients did
have a statistically significant risk factor
for developing pancreatic
cancer because of that
proportion of IGF-1 to IGFBP.
How do we
increase that proportion? By consuming an
abundance of dairy products.
Do people drinking milk have higher levels of
IGF-1? That question,
ironically, was answered
by a doctor who works for the dairy industry,
Robert Heaney at the University of Creighton.
Dr. Heaney's research
was published in the Journal
of the American Dietetic Association, vol.
10. October 1999. His conclusion:
"Serum IGF-I levels
increased significantly in milk
drinkers, an increase of about 10% above
but was unchanged in the control group."
The authors of
the British Journal of Cancer Study
did not make the above association
which may very
well be the key to understanding the etiology of
pancreatic cancer growth and proliferation in humans.