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Food for Thought for Pancreatic Cancer

A publication in the February 29, 2012 issue of the
British Journal of Cancer contains a previously
unexplored etiology for Pancreatic Cancer's growth.
(Br J Cancer. 2012 Feb 28;106(5):1004-10)

The study measured levels of insulin-like growth
factor-1 (IGF-1) and insulin-like growth factor
binding protein (IGFBP) in 844 subjects; 422
patients with pancreatic cancer, and 422 subjects
without cancer which made up the control group.

The researchers did not find a relationship with
IGF-I levels and pancreatic cancer, or with IGFBP
levels and pancreatic cancer, but they did find
a fascinating relationship between possible dairy
consumption and pancreatic cancer.

IGF-I has been identified as a key factor in the
growth of every human cancer. We naturally produce
IGF-I in many of our tissues and organs. We also
manufacture the binding site receptors for these
growth hormones to attach.

IGF-I is identical in humans and cows.

Bovine growth hormone (bGH) human growth hormone
(hGH) both have exactly 191 amino acids making up
their structure, but the sequence of those amino
acids differs between the two species by a factor
of 35 percent.

Human IGF-I and bovine IGF-1 both have 70 amino
acids in their structure, and miraculously, the
sequence of amino acids on their protein chains
is identical!

When we humans consume IGF-I in cow's milk, we do
so without also consuming the binding proteins
which are located within a cow's body.

So, our bodies become flooded with additional
IGF-1 which we manufacture, and there becomes
a dramatic proportional increase of IGF-I to
IGFBP in our own systems.

Here is the remarkable finding from the British
Journal of Cancer study.

Scientists found that pancreatic cancer patients
had extremely low levels of IGF binding protein in
relation to circulating IGF-1. These patients did
indeed have a statistically significant risk factor
for developing pancreatic cancer because of that
proportion of IGF-1 to IGFBP.

How do we increase that proportion? By consuming an
abundance of dairy products.

Do people drinking milk have higher levels of
IGF-1? That question, ironically, was answered
by a doctor who works for the dairy industry,
Robert Heaney at the University of Creighton.

Dr. Heaney's research was published in the Journal
of the American Dietetic Association, vol. 99, no.
10. October 1999. His conclusion:

"Serum IGF-I levels increased significantly in milk
drinkers, an increase of about 10% above baseline
but was unchanged in the control group."

The authors of the British Journal of Cancer Study
did not make the above association which may very
well be the key to understanding the etiology of
pancreatic cancer growth and proliferation in humans.

Food for Thought!

Robert Cohen

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